I don't have any experience with dual GPU cards but a couple of things to check.
On the calibration utility did you double click on the screen you want to use as your touch screen, the tick box on your pic above does not appear to show that enable multiple monitors is selected.
It may also be worth checking on the screen properties page that everything is OK [Touchscreen can be dragged to where you want it, does affect how mouse moves between screens]
Sorry if you have tried all this before - just clutching at straws im afraid.