I don't know what kind of drivers the Mimo uses. Does the Mimo use TouchKit drivers? You might need to
try new drivers, or
these old ones might work.
When you calibrate your touchscreen, it uses the current resolution of your monitors to calicate the coordinates of your touchscreen x/y position. But when a game resizes the main monitor the drivers are supposed to adjust for that. Sometimes they don't and your touch is then off.
You can try calibrating your touchscreen with the game monitor at the resolution of the game, so it does not resize it from where you calibrated it. But I think drives is the real solution.
WBK